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El anlisis del Broad Institute mostr que afecta al 31,2% de los genes, restableciendo los cambios genticos relacionados con la edad que contribuyen a la degeneracin de los tejidos

Biochem Pharmacol 88(4):640651 Roberts MS, Magnusson BM, Burczynski FJ, Weiss M (2002) Enterohepatic circulation: physiological, pharmacokinetic and clinical implications

For conditional MOR knockdown in PVN Glu neurons, we injected the rAAV-CMV-DIO-(EGFP-U6)-shRNA ( Oprm1 )-WPRE-hGH pA (AAV-DIO-shMOR-EGFP) virus or rAAV-CMV-DIO-(EGFP-U6)-shRNA(scramble)-WPRE-hGH polyA (AAV-DIO-EGFP) vector control into the bilateral PVN of VgluT2-Cre mice